SUPER-ENHANCER HIJACKING LINC01977 PROMOTES MALIGNANCY OF EARLY-STAGE LUNG ADENOCARCINOMA ADDICTED TO THE CANONICAL TGF-β/SMAD3 PATHWAY

Super-enhancer hijacking LINC01977 promotes malignancy of early-stage lung adenocarcinoma addicted to the canonical TGF-β/SMAD3 pathway

Abstract Background Lung adenocarcinoma (LUAD) is the leading cause of death worldwide.However, the roles of long noncoding RNAs (lncRNAs) hijacked by super-enhancers (SEs), vital regulatory elements of the epigenome, remain elusive in the progression of LUAD metastasis.Methods SE-associated lncRNA microarrays were used to identify the dysregulated

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Development of advanced cardiac progenitor cell culture system through fibronectin and vitronectin derived peptide coated plate

Cardiovascular disease remains a global health concern.Stem cell therapy utilizing human cardiac progenitor cells (hCPCs) shows promise in treating cardiac vascular disease.However, limited availability and senescence of hCPCs hinder their widespread use.To address these challenges, researchers are exploring innovative approaches.In this study, a b

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Educação em tempos de pandemia:

Inserido no tema de ensino em tempos de pandemia, este é um estudo bibliográfico exploratório da Comunicação Social que foi desenvolvido na Universidade Franciscana e aplicado diretamente ao corpo docente dos cursos de Publicidade e Propaganda e Jornalismo com o objetivo geral de compreender os impactos do Ensino Remoto – adotado pela instit

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